Cannabis tolerance develops because CB1 receptors — the brain's primary binding sites for THC — reduce in number and sensitivity with repeated exposure. The more consistently you use THC, the less responsive those receptors become, and the more you need to feel the same effect. The good news: tolerance is reversible. Even a short break resets sensitivity significantly.
Read MoreTHC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis. Discovered in 1964 by Dr. Raphael Mechoulam, THC works by binding to CB1 and CB2 receptors in your Endocannabinoid System (ECS), producing effects like euphoria, appetite stimulation, and pain relief. Dosage and your body chemistry both determine your experience.
Read MoreCBD (cannabidiol) is a non-psychoactive compound found in cannabis, first isolated in 1964 by Dr. Raphael Mechoulam. Unlike THC, CBD won't get you high. It interacts with your Endocannabinoid System — the body's largest receptor network — and may help with anxiety, pain, insomnia, and reducing alcohol cravings.
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