Why Is RSO So Powerful?
By Jeff Eckenrode
Image credit: Zach Reiner
RSO—short for Rick Simpson Oil—has become one of the most well-known and widely used cannabis extracts, especially among medical cannabis users.
Celebrated for its strong effects and wide range of applications, RSO is known for being incredibly potent. But what exactly makes RSO so powerful? And why do so many people turn to it for relief?
If you’ve ever wondered what sets RSO apart from other cannabis concentrates, then you’re in the right place!
Let’s break down what RSO is, how it’s made, and why it delivers such intense effects.
Image credit: Medizin Las Vegas
What is RSO?
RSO is a full-extract cannabis oil named after Canadian cannabis activist Rick Simpson, who originally created it as part of his personal cancer treatment regimen.
Unlike other concentrates that isolate specific cannabinoids like THC or CBD, RSO is made using the entire cannabis plant. This includes cannabinoids, terpenes, flavinoids, fats, chlorophyll, and other naturally occurring compounds.
The result? A thick, dark oil that packs a powerful punch—both in potency and therapeutic potential.
Image credit: Ryan Lange
RSO and Full-Spectrum Effects
One of the key reasons RSO is so powerful is that it’s a full-spectrum extract. That means it contains the full range of chemical compounds found in the cannabis plant—not just THC.
These compounds work together through what’s known as the entourage effect—a theory that cannabinoids and terpenes produce stronger, more balanced effects when consumed together rather than in isolation.
In short, RSO’s strength comes not just from high THC content, but from how all of the plant’s compounds combine to enhance one another.
Image credit: Diyahna Lewis
RSO’s Potent THC Content
RSO typically contains very high levels of THC—often 60–90% or more.
This is significantly higher than what you’d find in most cannabis flower (which averages around 15–25% THC) or even some concentrates.
This makes RSO especially effective for users seeking relief from severe symptoms such as chronic pain, insomnia, inflammation, or appetite loss.
Because of this high potency, new users are encouraged to start with very small doses—often just a grain-of-rice-sized amount.
Image credit: RUNGROJ YONGRIT
How RSO is Made
Another reason RSO is so powerful lies in how it’s made.
RSO is traditionally made by soaking cannabis flower in a strong solvent, like ethanol, to extract the plant’s medicinal compounds.
After soaking, the solvent is slowly evaporated, leaving behind a thick, tar-like oil rich in cannabinoids and other compounds.
Unlike more refined extracts (like distillate), RSO retains many of the raw plant’s natural materials, which contributes to its strength and full-body effects.
Because RSO uses the whole plant, it captures not only THC and CBD but also lesser-known cannabinoids like CBN, CBG, and others that may contribute to its powerful effects.
Image credit: The Hemp Mine
RSO and Medical Use
RSO is most commonly associated with medical cannabis treatment, and for good reason.
Its potency, full-spectrum composition, and versatility make it a popular choice for individuals managing conditions like:
Chronic pain
Cancer and chemotherapy side effects
Insomnia
Multiple sclerosis
Crohn’s disease
PTSD
It can be taken orally, applied topically, or infused into food—making it one of the most flexible cannabis products available.
Tolerance and Dosing with RSO
Because of its strength, RSO should be approached with caution—especially for beginners.
Many medical users follow a specific dosing regimen, starting with tiny doses and gradually increasing over time as the body builds tolerance. This helps avoid overwhelming effects while still experiencing the benefits of the oil.
Even experienced cannabis users may find RSO’s effects to be stronger and longer-lasting than expected.
Want to Learn More About Cannabis Extracts?
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Need help finding the right product or learning how to use RSO safely? Ask one of our knowledgeable budtenders!
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