By Lucas Kleven, Everett shift lead

As we learn more about cannabis, and restrictions are loosened around research, companies are finding more ways to integrate the newest cannabinoids into your favorite products. A couple years ago, we started seeing CBN offered as part of THC and CBD products, and about a year after that, CBG hit the market.

It can get confusing seeing all these cannabinoids and remembering which ones have what effects. We’re here to focus on what is currently the newest member of the crew: CBC!

Let’s learn more about CBC!

Cannabichromene, or CBC, is one of many cannabinoids found naturally occurring in the cannabis plant. Despite being found in abundance in many plants, there hasn’t been much research done about this cannabinoid. Its recent inclusion in products from edibles to pre-rolls coincides with the industry learning more and more about CBC.

CBC is often associated with sativas and sativa-hybrids due to the effects it tends to have when partnered with THC.

In my own experience, I find that CBC is a great mood booster and helps provide an extra giggle factor to the effects. I’ve also had guests mention that CBC tends to increase the euphoria they feel from their THC high.

How does CBC impact my health?

In terms of more health-focused benefits, many of our guests enjoy CBC for the same reason they enjoy CBD or CBG: strong anti-inflammatory effects. However, CBC brings along with it a few secret tools.

First: it’s also a pretty capable antinociceptive--meaning research has shown that CBC can help reduce the body’s reactivity to negative stimuli like pain or discomfort.
CBC is also remarkable due to its ability to provide therapeutic effects without directly interacting with your endocannabinoid system. It’s certainly stronger when used with THC and CBD, but its ability to target specific receptors related to pain allow it to cast a wider net in your nervous system and provide ample assistance to its other cannabinoid cousins.
As well, CBC has a higher rate of oral absorption compared to both THC and CBD. This helps to get those benefits to you as fast as possible!

So, to wrap things up in a nutshell, we can see that CBC has some great benefits, especially when paired with CBD, THC, or CBG. CBC is an ideal cannabinoid for those looking for a mood boost or something to further assist with inflammation and pain.

Where can I find CBC?

You can find CBC in varying amounts all across the product types, but for those looking for products that specifically test for higher percentages of CBC your best bet is to take a look at our edible selection.

Several companies have started offering specific flavors that contain CBC.

If you specifically want CBC, check out Wyld’s Blood Orange flavor or Green Revolution’s Strawberry Doozies. Both of these products have equal parts THC and CBC, so you can try and find out how CBC affects your edible effects.

If you like CBG and want to experiment, we have Wyld with their newest flavor: Grapefruit! It has CBG as well as THC and CBC.

If you’re trying to get as many cannabinoids as possible, look out for Sinners and Saints with their Mango Passion Fruit Gummies: THC, CBG, CBC, and CBD all in equal parts!

Try some edibles with CBC, and let us know what you think here in the comments!

Works cited

Calcaterra A, Cianfoni G, Tortora C, Manetto S, Grassi G, Botta B, Gasparrini F, Mazzoccanti G, Appendino G. Natural cannabichromene (CBC) shows distinct scalemicity grades and enantiomeric dominance in Cannabis sativa strains. Journal of Natural Products 2023 86 (4), 909-914. DOI: 10.1021/acs.jnatprod.2c01139

“CBC.” Cresco Labs. June 19, 2024. https://www.crescolabs.com/cannabinoids/cbc/

DeLong GT, Wolf CE, Poklis A, Lichtman AH. Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol. Drug Alcohol Depend. 2010 Nov 1;112(1-2):126-33. doi: 10.1016/j.drugalcdep.2010.05.019. PMID: 20619971; PMCID: PMC2967639.

Izzo AA, Capasso R, Aviello G, Borrelli F, Romano B, Piscitelli F, Gallo L, Capasso F, Orlando P, Di Marzo V. Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. Br J Pharmacol. 2012 Jun;166(4):1444-60. doi: 10.1111/j.1476-5381.2012.01879.x. PMID: 22300105; PMCID: PMC3417459.

Maione S, Piscitelli F, Gatta L, Vita D, De Petrocellis L, Palazzo E, de Novellis V, Di Marzo V. Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action. Br J Pharmacol. 2011 Feb;162(3):584-96. doi: 10.1111/j.1476-5381.2010.01063.x. PMID: 20942863; PMCID: PMC3041249.

Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. PMID: 21749363; PMCID: PMC3165946.

Turner CE, Elsohly MA. Biological activity of cannabichromene, its homologs and isomers. J Clin Pharmacol. 1981 Aug-Sep;21(S1):283S-291S. doi: 10.1002/j.1552-4604.1981.tb02606.x. PMID: 7298870.

Udoh M, Santiago M, Devenish S, McGregor IS, Connor M. Cannabichromene is a cannabinoid CB2 receptor agonist. Br J Pharmacol. 2019 Dec;176(23):4537-4547. doi: 10.1111/bph.14815. Epub 2019 Nov 21. PMID: 31368508; PMCID: PMC6932936.

What is CBC?

Let’s learn more about CBC!

How does CBC impact my health?

Where can I find CBC?

Works cited